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4',7-Dimethoxy-5-Hydroxyflavone 98% (CAS: 5128-44-9): A High-Purity Flavonoid for Research, Analysis & Ingredient Development

4',7-Dimethoxy-5-Hydroxyflavone 98% (CAS: 5128-44-9): A High-Purity Flavonoid for Research, Analysis & Ingredient Development

December 11, 2025

4',7-Dimethoxy-5-Hydroxyflavone 98% (CAS: 5128-44-9): A High-Purity Flavonoid for Research, Analysis & Ingredient Development

December 2025

Introduction

4',7-Dimethoxy-5-Hydroxyflavone (CAS: 5128-44-9) is a naturally occurring flavonoid found in several botanical species. With its well-defined molecular structure and high analytical value, this compound has become a preferred standard in phytochemistry, flavonoid research, and ingredient development.

At Nanjing Spring & Autumn Biological Engineering Co., Ltd., we supply 4',7-Dimethoxy-5-Hydroxyflavone ≥98% (HPLC), manufactured under strict quality control with full supporting documentation. This research-grade material is ideal for universities, laboratories, cosmetic ingredient developers, and natural product research institutions.


What Is 4',7-Dimethoxy-5-Hydroxyflavone?

4',7-Dimethoxy-5-Hydroxyflavone is a polymethoxyflavone featuring two methoxy groups and one hydroxyl group, contributing to its stable chemical properties and suitability for advanced analytical and structural studies.

This compound is commonly applied in:

  • Natural product identification and quantification

  • Reference standard preparation for analytical testing

  • Quality control of botanical extracts

  • Flavonoid comparison studies and ingredient characterization

  • R&D formulation and process development

Our product is strictly intended for scientific research, laboratory analysis, and formulation development, not for direct consumption or medical applications.


Chemical Information

Item Detail
Product Name 4',7-Dimethoxy-5-Hydroxyflavone
CAS Number 5128-44-9
Molecular Formula C??H??O?
Molecular Weight 298.29 g/mol
Appearance Yellow to light-yellow crystalline powder
Purity ≥98% (HPLC)
Botanical Origin Plant-derived flavonoid

Product Characteristics

High Research-Grade Purity

Each batch is verified via HPLC to ensure ≥98% purity with clear impurity profiles suitable for analytical use.

Natural Botanical Origin

This flavonoid is extracted and purified from plant materials through controlled processes to ensure stable quality and reproducibility.

Stable & Convenient for Laboratory Use

The product features a fine crystalline texture and is stored at 2–8°C, protected from light, ensuring long-term stability.

Complete Documentation Provided

All shipments include:

  • Certificate of Analysis (COA)

  • HPLC Chromatogram

  • MS and NMR Data

  • MSDS

  • Technical Data Sheet (TDS)


Applications in Research and Industry

1. Phytochemical Research

As a structurally relevant flavonoid, 4',7-Dimethoxy-5-Hydroxyflavone is widely used in natural product chemistry, flavonoid profiling, and structural elucidation studies.

2. Analytical Method Development

Ideal for establishing and validating analytical methods including:

  • HPLC

  • LC-MS/MS

  • UV-Vis quantification

  • Chromatographic fingerprinting

3. Botanical Extract Standardization

Used as a marker compound or quality control standard in evaluating plant extracts rich in polymethoxyflavones.

4. Cosmetic Ingredient Screening

Serves as a research ingredient for evaluating plant-based raw material characteristics, formulation behavior, and stability.


Technical Specifications

Parameter Specification
Purity ≥98% (HPLC)
Melting Point 180–185°C (typical range)
Solubility Soluble in DMSO, ethanol
Storage 2–8°C, protected from light
Shelf Life 36 months

Packaging Options

Packaging Size Recommended Use
10 g Analytical or small-scale research
25 g Laboratory research projects
100 g Pilot-scale R&D
500 g – 1 kg Industrial formulation research

Each batch is packed in moisture-protective, sealed containers to ensure stability during transport and storage.


Why Choose Nanjing Spring & Autumn Biological Engineering Co., Ltd.?

1. Strict Quality Assurance

All materials undergo comprehensive in-house and third-party testing to guarantee consistent purity and analytical reliability.

2. Full Technical Support and Documentation

We provide complete data packages including COA, HPLC, MS, NMR, and safety documentation.

3. Stable Global Supply

Our facility maintains long-term stock and efficient production capacity for uninterrupted supply.

4. Custom Packaging & Bulk Support

We accommodate small trial quantities as well as large R&D or industrial-level orders.

5. Worldwide Shipping Capability

International customers benefit from compliant export documentation and temperature-controlled packaging where required.


Conclusion

4',7-Dimethoxy-5-Hydroxyflavone (CAS: 5128-44-9) is a valuable research-grade flavonoid widely used in natural product chemistry, botanical analysis, and ingredient development. With ≥98% purity, reliable quality, and full analytical documentation, Nanjing Spring & Autumn Biological Engineering Co., Ltd. is committed to supporting global research and industrial partners requiring premium-grade natural compounds.

For quotations, technical files, or sample requests, please contact us anytime.


 

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