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December 2025
4',7-Dimethoxy-5-Hydroxyflavone (CAS: 5128-44-9) is a naturally occurring flavonoid found in several botanical species. With its well-defined molecular structure and high analytical value, this compound has become a preferred standard in phytochemistry, flavonoid research, and ingredient development.
At Nanjing Spring & Autumn Biological Engineering Co., Ltd., we supply 4',7-Dimethoxy-5-Hydroxyflavone ≥98% (HPLC), manufactured under strict quality control with full supporting documentation. This research-grade material is ideal for universities, laboratories, cosmetic ingredient developers, and natural product research institutions.

4',7-Dimethoxy-5-Hydroxyflavone is a polymethoxyflavone featuring two methoxy groups and one hydroxyl group, contributing to its stable chemical properties and suitability for advanced analytical and structural studies.
This compound is commonly applied in:
Natural product identification and quantification
Reference standard preparation for analytical testing
Quality control of botanical extracts
Flavonoid comparison studies and ingredient characterization
R&D formulation and process development
Our product is strictly intended for scientific research, laboratory analysis, and formulation development, not for direct consumption or medical applications.
| Item | Detail |
|---|---|
| Product Name | 4',7-Dimethoxy-5-Hydroxyflavone |
| CAS Number | 5128-44-9 |
| Molecular Formula | C??H??O? |
| Molecular Weight | 298.29 g/mol |
| Appearance | Yellow to light-yellow crystalline powder |
| Purity | ≥98% (HPLC) |
| Botanical Origin | Plant-derived flavonoid |
Each batch is verified via HPLC to ensure ≥98% purity with clear impurity profiles suitable for analytical use.
This flavonoid is extracted and purified from plant materials through controlled processes to ensure stable quality and reproducibility.
The product features a fine crystalline texture and is stored at 2–8°C, protected from light, ensuring long-term stability.
All shipments include:
Certificate of Analysis (COA)
HPLC Chromatogram
MS and NMR Data
MSDS
Technical Data Sheet (TDS)

As a structurally relevant flavonoid, 4',7-Dimethoxy-5-Hydroxyflavone is widely used in natural product chemistry, flavonoid profiling, and structural elucidation studies.
Ideal for establishing and validating analytical methods including:
HPLC
LC-MS/MS
UV-Vis quantification
Chromatographic fingerprinting
Used as a marker compound or quality control standard in evaluating plant extracts rich in polymethoxyflavones.
Serves as a research ingredient for evaluating plant-based raw material characteristics, formulation behavior, and stability.

| Parameter | Specification |
|---|---|
| Purity | ≥98% (HPLC) |
| Melting Point | 180–185°C (typical range) |
| Solubility | Soluble in DMSO, ethanol |
| Storage | 2–8°C, protected from light |
| Shelf Life | 36 months |
| Packaging Size | Recommended Use |
|---|---|
| 10 g | Analytical or small-scale research |
| 25 g | Laboratory research projects |
| 100 g | Pilot-scale R&D |
| 500 g – 1 kg | Industrial formulation research |
Each batch is packed in moisture-protective, sealed containers to ensure stability during transport and storage.
All materials undergo comprehensive in-house and third-party testing to guarantee consistent purity and analytical reliability.
We provide complete data packages including COA, HPLC, MS, NMR, and safety documentation.
Our facility maintains long-term stock and efficient production capacity for uninterrupted supply.
We accommodate small trial quantities as well as large R&D or industrial-level orders.
International customers benefit from compliant export documentation and temperature-controlled packaging where required.
4',7-Dimethoxy-5-Hydroxyflavone (CAS: 5128-44-9) is a valuable research-grade flavonoid widely used in natural product chemistry, botanical analysis, and ingredient development. With ≥98% purity, reliable quality, and full analytical documentation, Nanjing Spring & Autumn Biological Engineering Co., Ltd. is committed to supporting global research and industrial partners requiring premium-grade natural compounds.
For quotations, technical files, or sample requests, please contact us anytime.