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Natural Betulonic Acid (Liquidambaric Acid) CAS 4481-62-3 | Anti-Tumor Triterpenoid for Melanoma Research
Betulonic Acid (CAS 4481-62-3), also known as Liquidambaric Acid, is a natural triterpenoid compound derived from Liquidambar species. It exhibits potent anti-tumor activity against melanoma, induces cancer cell apoptosis, and inhibits angiogenesis. With high purity (HPLC≥98%) and solubility in DMSO/chloroform, it is widely used in pharmaceutical research and reference standards.
Product Name :
Betulonic AcidCAS No. :
4481-62-3Appearance :
White crystalline powderSpecification :
98%CAS No.: 4481-62-3
Molecular Formula: C??H??O?
Molecular Weight: 454.70

Key Intermediate for Anticancer Triterpenoids & Metabolic Regulator
≥99% Pure: White crystalline powder (HPLC-Validated Pharma Grade)
Mechanism-Confirmed Benefits:
Anticancer Prodrug
Anti-Adipogenic Action
Anti-Adipogenic Action
Hepatoprotective
| Parameter | Detail |
|---|---|
| Purity | ≥98% (HPLC-ELSD) |
| Identification | HPLC-UV/ELSD, ¹³C-NM |
| Solubility | Soluble in chloroform, DMSO, acetone; insoluble in water (<0.001 g/L) |
| Melting Point | 292-295°C |
| Specific Rotation | +10° (c=1, CHCl?) |
| Storage | 2–8°C (desiccated, amber glass; avoid light) |
| Shelf Life | 24 months |
| Industry | Use Cases |
|---|---|
| Pharmaceuticals | - Anticancer prodrug synthesis (C28-amide derivatives) - NAFLD/NASH therapeutic leads |
| Cosmeceuticals | - Anti-cellulite formulations (adipogenesis inhibition) - Redness-reducing serums |
| Nutraceuticals | - Liver detox supplements - Metabolic syndrome support |
| Agrochemicals | - High-purity intermediate for betulinic acid APIs |
Derivative Synthesis Platform:
Metabolic Dual Action:
Sustainable Sourcing:
Regulatory Edge:
| Goods weight |
Packing |
Shipping method |
Lead-time |
| 1–100 mg |
Amber glass vials (vacuum-sealed) |
Dry ice express |
3~5 days after your payment |
| 100 mg–1k g |
Aluminum foil bags (O? absorber) |
Air shipping | 3~5 days after your payment |
| >1k g |
Steel drums (nitrogen flushed) |
Air shipping |
5~7 days after your payment |

Q1: Could you provide free samples for test?